Embryionic formation of the vagina

Most human anomalies may be represented in other species so that some authors consider them to be atavistic reversions. The prostatic embryionic formation of the vagina is a homologue of the uterus and upper vagina and may be involved in similar deranged developments. It elaborates androgenic steroids and a polypeptide, a Mullerian inhibiting substance, which induced suppression and resorotion of the Mullerian ducts.

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Embryionic formation of the vagina
Embryionic formation of the vagina

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The embryologic development of the human vagina.

These, together with the urogenital sinus and the metanephric ducts, provide the tissue sources for the internal genital and urinary apparatus, exclusive of the gonads and kidneys. It elaborates androgenic steroids and a polypeptide, a Mullerian inhibiting substance, which induced suppression and resorotion of the Mullerian ducts. The abnormalities recently described in the vagina and cervix of girls exposed in utero to diethylstilbestrol DES correspond remarkably with those encountered in lower vaginal agenesis, particularly with regard to the presence of vaginal adenosis, the deficiency of glycogen in the squamous cells squamous metaplasiaand the abnormal response of the squamous epithelium to Schiller's iodine test. Both Mullerian tissue and that of embryionic formation of the vagina urogenital sinus origin normally participate in the development of the vagina. Most human anomalies may be represented in other species so that some authors consider them to be atavistic reversions.

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Embryionic formation of the vagina
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Embryionic formation of the vagina
Embryionic formation of the vagina
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The adenosis, areas of squamous metaplasia, and deformities of the cervix of girls exposed in utero to diethylestibestrol are examples of deranged development. The development of the external genitals and secondary sex characteristics depends upon further exposure to androgenic or estrogenic hormone milieu. Most human anomalies may be represented in other species so that some authors consider them to be atavistic reversions.

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Embryionic formation of the vagina
Embryionic formation of the vagina
Embryionic formation of the vagina

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